Concentration, time to appearance and duration of detection of cannabinoids in the blood after smoking
THC is fat soluble and readily spreads in the innervated tissues of the brain; it reaches a peak in the blood plasma in less than nine minutes and falls to approximately 5% after one hour.
The body is slow to eliminate THC and inactive THC metabolites can be detected in urine up to 27 days after use in the case of regular users.
Concentration, time to appearance and duration of detection of cannabinoids in the blood after smoking a marijuana cigarette containing 15.8 mg or 33.8 mg of D9THC
Component; |
Maximum concentration |
Time to appearance
of peak (hr) |
Duration of detection
(hr) |
|
D9THC |
84,3 (50-129) (3) 162,2 (76-267) (4) |
0,14 (0,10-0,17) 0,14 (0,08-0,17) |
7,3 (3-12) 12,5 (6-27) |
|
11-OH-D9THC |
6,7 (3,3-10,4) 7,5 (3,8-16,0) |
0,25 (0,15-0,38) 0,20 (0,15-0,25) |
4,5 (0,54-12) 11,2 (2,2-27) |
|
D9THC-COOH |
24,5 (15-54) 54,0 (22-101) |
2,43 (0,8-4,0) 1,35 (0,54-2,21) |
84,0 (48-168) 152,0 (72-168) |
(1) average interval between start of consumption and appearance of a concentration peak
(2) average interval between start of consumption and moment when lowest concentration of component is detected (> 0.5 mg/ml)
(3) cigarette containing 13.8 mg (1.75%) of D9THC
(4) cigarette containing 33.8 mg (3.55%) of D9THC
Source : www.parl.gc.ca
http://www.parl.gc.ca/37/1/parlbus/commbus/senate/Com-e/ille-e/rep-e/repfinalvol1part1-e.htm