Is cannabis definitely not a causal factor for schizophrenia?
Israelian scientists propose that the association between cannabis use and increased risk for schizophrenia that have been observed in recent studies from Sweden, the Netherlands, New Zealand, and Israel may not be causal. Several studies have reported an association between genes encoding the cannabinoid receptor and schizophrenia.
The researchers write: "An alternative explanation of the association between cannabis use and schizophrenia might be that pathology of the cannabinoid system in schizophrenia patients is associated with both increased rates of cannabis use and increased risk for schizophrenia, without cannabis being a causal factor for schizophrenia."
(Weiser M, Noy S. Dialogues Clin Neurosci. 2005;7(1):81-5.)